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An understanding of disease processes drives innovation in medicine

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"A thinker sees his own actions as experiments
and questions, as attempts to find out something.
Success and failure are for him answers above all."

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"There is one thing even more vital to science than intelligent
methods; and that is the sincere desire to find out the truth,
whatever it may be."

- Charles Pierce

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"Every great advance in science has issued
from a new audacity of imagination"

- John Dewey

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"Somewhere, something incredible is waiting to be known"

- Carl Sagan

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"There is nothing which can better deserve your patronage
than the promotion of science and literature. Knowledge is in every country the surest basis of public happiness."

- George Washington

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"Learn from yesterday, live for today, hope for tomorrow
The important thing is to not stop questioning."

- Albert Einstein

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Welcome

Welcome to the website of the CellCOM Research Group. Our group is a translational and clinical research group within the Institute of Biomedical Research of A Coruña (INIBIC), part of the University Hospital Complex A Coruña, which provides a strong clinical basis for laboratory-based research. Our approaches combine in vitro, ex vivo and in vivo models to conduct pre-clinical studies in age-related diseases and cancer. Our group is a multidisciplinary team that includes basic scientists (predoctoral, postdoctoral fellows and technicians) and clinical researchers such as pathologists, dermatologists, radiologists and surgeons.

Our aims are to understand the physiopathology of connexin-linked diseases (cancer, inflammation, tissue degeneration), to design molecules and new drugs that modulate the activity of specific targets and to identify novel markers of disease prevention, diagnosis and disease management.

We are focused on understanding the role of connexins and pannexins in osteoarthritis, skin wound healing in oncological patients, metastasis and resistance to targeted cancer therapies and immunotherapies. Our final goal is to identify effective therapeutic targets to design specific and successful therapeutic approaches to treat these disorders.

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New PhD thesis in the group

New PhD thesis in the group

Dic 14, 2018

Sept 2018 Marta Varela has successfully defended her PhD thesis on September 22 in CHUAC-XXIAC (INIBIC) Congratulations Marta!! You did such a good job in order to understand the mechanism…

New results published in Cell Death and Disease

New results published in Cell Death and Disease

Nov 22, 2018

Dec 2018 Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Full text. Thanks to our collaborators and congratulations Marta Varela! Good job!!…

Seminars INIBIC (CHUAC-XXIAC) and CICA with Marisol Soengas and Lluís Montoliu

Seminars INIBIC (CHUAC-XXIAC) and CICA with Marisol Soengas and Lluís Montoliu

Oct 3, 2018

May – Sept 2018 We have enjoyed time with Marisol Soengas, Lluís Montoliu, Manuel Irimia, Silvia Penuela and Frank Beier Our group actively participates in the organization of seminars and…

Publication in the main science divulgation journal in Spain.

Publication in the main science divulgation journal in Spain.

Oct 3, 2018

March 2018 Publication in the main science divulgation journal in Spain. Images of of Marta Varela Eirín. Marta Varela-Eirin & Maria D. Mayan. Uniones celulares comunicantes. Investigación y Ciencia. Marzo 2018 (42-43).…

Connexin and pannexin channels in inflammation and cancer

Connexin and pannexin channels in inflammation and cancer

Sep 26, 2018

Sept 2018 Science Xpression 2018 Sixth edition of Science Xpression workshop organised by our group in collaboration with Susana Sangiao and other collaborators. We have enjoyed  the session of conferences…

New results published in BBA-Biomembranes

New results published in BBA-Biomembranes

Sep 20, 2018

Sept 2018 Intercellular communication via gap junction channels between chondrocytes and bone cells Congratulations Paula Carpintero! Ready for the next paper? We have demonstrated in collaboration with Virgis Valiunas and…