Welcome
Welcome to the website of the CellCOM Research Group. Our group is a translational and clinical research group within the Center for Research in Nanomaterials and Biomedicine (CINBIO). Our approaches combine in vitro, ex vivo and in vivo models to conduct pre-clinical studies in age-related diseases and cancer. Our group is a multidisciplinary team that includes basic scientists (predoctoral, postdoctoral fellows and technicians) and clinical researchers such as pathologists, dermatologists, radiologists and surgeons.
Our aims are to understand the physiopathology of connexin-linked diseases (cancer, inflammation, tissue degeneration), to design molecules and new drugs that modulate the activity of specific targets and to identify novel markers of disease prevention, diagnosis and disease management.
We are focused on understanding the role of connexins and pannexins in osteoarthritis, skin wound healing in oncological patients, metastasis and resistance to targeted cancer therapies and immunotherapies. Our final goal is to identify effective therapeutic targets to design specific and successful therapeutic approaches to treat these disorders.
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Latest news
New PhD thesis in the group
Sept 2018 Marta Varela has successfully defended her PhD thesis on September 22 in CHUAC-XXIAC (INIBIC) Congratulations Marta!! You did such a good job in order to understand the mechanism…
New results published in Cell Death and Disease
Dec 2018 Targeting of chondrocyte plasticity via connexin43 modulation attenuates cellular senescence and fosters a pro-regenerative environment in osteoarthritis. Full text. Thanks to our collaborators and congratulations Marta Varela! Good job!!…
Seminars INIBIC (CHUAC-XXIAC) and CICA with Marisol Soengas and Lluís Montoliu
May – Sept 2018 We have enjoyed time with Marisol Soengas, Lluís Montoliu, Manuel Irimia, Silvia Penuela and Frank Beier Our group actively participates in the organization of seminars and…
Publication in the main science divulgation journal in Spain.
March 2018 Publication in the main science divulgation journal in Spain. Images of of Marta Varela Eirín. Marta Varela-Eirin & Maria D. Mayan. Uniones celulares comunicantes. Investigación y Ciencia. Marzo 2018 (42-43).…
Connexin and pannexin channels in inflammation and cancer
Sept 2018 Science Xpression 2018 Sixth edition of Science Xpression workshop organised by our group in collaboration with Susana Sangiao and other collaborators. We have enjoyed the session of conferences…
New results published in BBA-Biomembranes
Sept 2018 Intercellular communication via gap junction channels between chondrocytes and bone cells Congratulations Paula Carpintero! Ready for the next paper? We have demonstrated in collaboration with Virgis Valiunas and…